Model Organisms & Agents

Back to homepage
View "Model Organisms & Agents" category tree  

Complement Factor H Knock Out Mouse Model

Disease model for research into conditions involving complement factor H

Compliment Factor H knock-out mice. Unique pre-evaluated model for Age-related Macular Degeneration. 

VIEW PRODUCT

Mouse model expressing human ICAM-1

Disease model for Rhinoviruses

BALB/c strain transgenic disease mouse model for rhinovirus-binding extracellular domains 1 and 2 of human ICAM-1. 

VIEW PRODUCT

Charcot-Marie Tooth Disease model

Models for Charcot-Marie Tooth Disease

Model for Charcot-Marie Tooth disease type1A constructed by pronuclear injection of a YAC containing the human PMP22 gene.

VIEW PRODUCT

Human ZnT8/luc mouse (tetracyclin-inducible)

Mouse expresses human zinc transporter 8

Mouse model expressing human zinc transporter 8 (ZnT8) and firefly luciferase. ZnT8 is expressed prinicpally in pancreatic islet cells and is of interest in diabetes research. Expression of ZnT8/luc in this model is induced by tetracycline.

VIEW PRODUCT

RSV A2 strain

Respiratory syncytial virus strain A2 sub-clone

Respiratory syncytial Virus (RSV) strain A2 sub-clone selected for mouse infection.

VIEW PRODUCT

DR15 and a MBP (84-102)-specific T cell receptor (TCR) mouse

Transgenic multiple sclerosis model

Mouse model co-expressesing HLA-DR15 and a human MS patient derived T-cell receptor, specific for HLA-DR15/MBP 85-99. Mice display spontaneous disease allowing analysis of CNS pathology and immunology that is faithful to clinical multiple sclerosis.

VIEW PRODUCT

POPDC1S191F zebrafish mutant

Zebrafish mutant for cardiac arrhythmia

popdc1-null (popdc1E2 line). Exhibits reduced cAMP binding associated with cardiac arrhythmia, muscular dystrophy and myofiber rupture and models a mutation found in patients with limb-girdle muscular dystrophy and AV-block.


VIEW PRODUCT