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Rabbit anti-human cytochrome P450 enzymes CYP2C8/9/19 and rat CYP2C12 (polyclonal antibody). CYP2C8/9/19 are three of the four main human epoxygenases - key in fatty acid metabolism. Covert arachidonic acid to epoxyeicosatrienoic acids (EETs), which are believed to have protective effects on the cardiovascular system1.

CODE NUMBER: RK03.

QUANTITY: 0.1 mL.

SPECIFICITY: Reacts with cytochrome P450 CYP2C8, CYP2C9 and CYP2C19 in human hepatic microsomal fraction and to CYP2C12 in rat hepatic microsomal fraction.

IMMUNOGEN: Synthetic peptide.

SUGGESTED APPLICATIONS: Western blot, immunohistochemistry on frozen and formaldehyde treated sections. Optimal working dilutions must be determined by end user.

SPECIES REACTIVITY: Human, rat.

FORMAT: Rabbit antiserum.

PRESENTATION: Liquid. No preservatives.

STORAGE/HANDLING: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

For research use only; not for use in diagnostic procedures. Not for human or animal consumption.

CYP2C8 is also known as CPC8, CYPIIC8, MP-12/MP-20
CYP2C9 is also known as CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
CYP2C19 is also known as CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
CYP2C12 is also known as CYPIIC12, Cyp2c-12, Cyp2c40

 

 

To purchase this antibody, please contact quicktech@imperialinnovations.co.uk

 

1. Shahabi et al. (2014) Human cytochrome P450 epoxygenases: Variability in expression and role in inflammation-related disorders, Pharmacology & Therapeutics 144(2): 134-161

 

Internal case number: 1612

PAb for human cytochrome P450 CYP2C8/9/19 and rat CYP2C12

Polyclonal antibody for human cytochrome P450 enzymes CYP2C8/9/19 and rat CYP2C12, raised in rabbits

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General POA Licence 0.10

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Further details
Term: perpetual (does not require renewal)
Seats: n/a

Price excl. VAT: P.O.A. (price on application)

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