• DESCRIPTION
  • FILES (0)
  • REFERENCES (1)
  • SUPPORT

Heme-thiolate monooxygenase, involved in metabolism of several steroids, fatty acids, and xenobiotics. CYP3A4 & 5 are the two most predominant proteins within the CYP3A subfamily in human adults, which are collectively involved with the biotransformation of 50% of oxidatively metabolised drugs1.

DESCRIPTION: Rabbit anti-human cytochrome P450 enzyme CYP3A5 (polyclonal antibody).

CODE NUMBER: R3M.

QUANTITY: 0.1 mL.

SPECIFICITY:  Reacts with human cytochrome P450 enzyme CYP3A5 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes including CYP3A4.

IMMUNOGEN:  Synthetic peptide.

SUGGESTED APPLICATIONS:  Western blot, immunohistochemistry on frozen and formaldehyde treated sections. Optimal working dilutions must be determined by end user.

SPECIES REACTIVITY:  Human.

FORMAT:  Rabbit antiserum.

PRESENTATION:  Liquid. No preservatives.

STORAGE/HANDLING:  Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

For research use only; not for use in diagnostic procedures. Not for human or animal consumption.

CYP3A5 is also known as CP35, CYPIIIA5, P450PCN3 and PCN3 

 

 

To purchase this antibody, please contact quicktech@imperialinnovations.co.uk

 

 

Antibodies specific to the following related cytochrome P450 species are also available:

 

 

1. Williams et al. (2002) Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7, Drug Metabolism and Disposition 30(8): 883-91

 

Internal case number: 1612

Polyclonal antibody for human CYP3A5

Specific to human cytochrome P450 enzyme CYP3A5, raised in rabbits

OPTIONS
Please check carefully that the terms you select correspond to your intended use of the product.

General POA Licence 0.10

View Terms

Further details
Term: perpetual (does not require renewal)
Seats: n/a

Price excl. VAT: P.O.A. (price on application)

Please contact us before adding this licence to your basket.