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Rabbit anti-rat cytochrome P450 enzymes CYP1A1 and CYP1A2 (polyclonal antibody). Involved in metabolism of xenobiotics, drugs and polyunsaturated fatty acids. Implicated in metabolism of some polycyclic hydrocarbons to carcinogenic intermediates. 



SPECIFICITY:  Reacts with rat cytochrome P450 enzymes CYP1A1 and CYP1A2 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes.

IMMUNOGEN:  Synthetic peptide.

SUGGESTED APPLICATIONS:  Western blot: useful for the simultaneous detection of rat CYP1A1 (57 kDa) and CYP1A2 (54 kDa), which can be separated by SDS-polyacrylamide electrophoresis. Immunohistochemistry on frozen and formaldehyde treated sections. Optimal working dilutions must be determined by end user.


FORMAT:  Rabbit antiserum.

PRESENTATION:  Liquid. No preservatives.

STORAGE/HANDLING:  Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

For research use only; not for use in diagnostic procedures. Not for human or animal consumption.

CYP1A1 is also known as AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX and CYPIA1
CYP1A2 is also known as CP12, P3-450 and P450(PA)


To purchase this product, please email quicktech@imperialinnovations.co.uk



Antibodies specific to the following related cytochrome P450 species are also available:


Internal case number: 1612

PAb for rat Cytochrome P450 enzymes CYP1A1 & CYP1A2

Polyclonal antibody for rat Cytochrome P450 CYP1A1 and CYP1A2 enzymes, raised in rabbits

Please check carefully that the terms you select correspond to your intended use of the product.

General POA Licence 0.10

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Further details
Term: perpetual (does not require renewal)
Seats: n/a

Price excl. VAT: P.O.A. (price on application)

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